Scientific evidence for the benefits of MFGM to brain development and cognitive function

Numerous randomized, controlled trials have investigated the effect of supplementing MFGM, complex milk lipids, or MFGM components in infants and children. Aligned with preclinical research, the majority of these studies have shown evidence of the benefits in cognition, behavior, immune system development, and gut health. Many trials have specifically focused on supporting brain development by adding MFGM components like gangliosides and sphingomyelin (SM) to the diets of pediatric populations across various age groups.

The following table summarizes the clinical studies reporting the role of Milk Fat Globule Membrane components in supporting brain myelination, cognitive function, and social-emotional function in infants and children offering valuable insights into the potential benefits of incorporating MFGM into infant nutrition.